Impaired autophagy contributes to the aggravated deterioration of osteoarthritis articular cartilage by peroxisome proliferator-activated receptor α deficiency, associated with decreased ERK and Akt activation

Abstract Background Although the chondroprotection of peroxisome proliferator-activated receptor ? (PPAR?) activation against osteoarthritis (OA) has been revealed, the regulatory mechanism of PPAR? deficiency to aggravate osteoarthritic cartilage deterioration remains unclear.Here, we aimed to investigate whether and how autophagy is involved in O

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Role of immune response in Yersinia pestis infection

Yersinia pestis (Y.Pestis) is an infamous pathogen causing plague pandemics throughout history and is a selected agent of bioterrorism threatening public health.Y.pestis was first isolated by Alexandre Yersin in 1894 in Hong Kong and in the years to follow from all continents.Plague is enzootic in different rodents and their fleas in Africa, Toddle

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Insecticidal potentials of plant oils against Callosobruchus chinensis (Coleoptera: Bruchidae) in stored chickpea

Pulse beetle, Callosobruchus chinensis L., is an important pest of stored chickpea and widely distributed in the world.Chemical insecticides and fumigants are common control tactics against pulse beetle, even though they have glassware caused serious drawbacks.As an alternative control method, botanical compounds and their constituents have been su

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Application of Hyperspectral Technology Combined With Bat Algorithm-AdaBoost Model in Field Soil Nutrient Prediction

This paper proposes a glassware hyperspectral soil nutrient estimation method based on the bat algorithm (BA)-AdaBoost model.The spectral reflectance, the first derivative of the reflectance, and the reciprocal logarithm of the reflectance are analyzed based on the 800 field soil samples and their hyperspectral data collected.The first derivative o

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